To check for the ability of sST2 to predict advanced liver fibrosis (i.e., F3/F4 fibrosis), we derived ROC curves with area under the ROC curve (AUROC) for APRI, FIB-4, CK-18 and sST2 from values before treatment in patients with SVR. The gene discussed is KRT18; the disease is Hepatic fibrosis.