STING1 and head and neck squamous cell carcinoma: On the other hand, autophagy impairment in tumor cells may lead to decreased antigen presentation (Zhong et al. 2016; Münz 2021; Jiang et al. 2021b) and an increased degradation of STING by HPV16 could help the HNSCC cells evade the immune system (Luo et al. 2020).