SON and multiple congenital anomalies/dysmorphic syndrome-intellectual disability: Besides characterizing the clinical features mentioned above, we highlighted hematopoietic features of Son+/– mice, which are closely linked to the symptoms found in ZTTK syndrome, including leukopenia, macrocytosis, and thrombocytopenia, and identified the altered hematopoietic lineage differentiation in Son+/– mice.