To validate sensitivity towards the known genes implicated in phenotypic switching of SMCs in atherosclerosis, we confirmed that markers of synthetic SMCs (Fn1, Col1a1, Col3a1, Col1a2, Eln, and Vcam1) were elevated in SMCTRAP-AS compared with SMCTRAP (Figure 2C). The gene discussed is COL1A2; the disease is atherosclerosis.