The gene list included well-known atherosclerosis-associated genes Serpina3,42Cemip,43Thbs1,44Lum,45 and Spp146,47 but also novel genes without previous association to SMC function in atherosclerosis, such as Anxa4, Cd276, Itih4, Myof, Pcdh11x, Rab31, Serpinb6b, Slc35e4, Slc8a3, and Spink5 (see Supplementary material online, Table S17). Here, SPINK5 is linked to atherosclerosis.