Subsequently, we confirmed the upregulation of PERIOSTIN pathway-related protein POSTN expression in pathological sections (Supplementary Table 5; Psoriasis/Normal skin Ratio in POSTN protein: 0.813 (or Normal/Psoriasis skin Ratio in POSTN protein: 1.230), Psoriasis/Normal skin Ratio in ITGAV protein: 0.938 (or Normal/Psoriasis skin Ratio in ITGAV protein: 1.066), Psoriasis/Normal skin Ratio in ITGB5 protein: 0.614 (or Normal/Psoriasis skin Ratio in ITGB5 protein: 1.629)). This evidence concerns the gene ITGB5 and psoriasis.