To elucidate the role of MC-produced mediators in the pathology of atherosclerosis, they used an adoptive transfer strategy using MCs obtained from either syngeneic WT, IL-6−/−, IFNγ−/−, or TNFα−/− mice to restore atherogenesis in Ldlr–/–KitW−sh/W−sh mice. Here, LDLR is linked to atherosclerosis.