To control for confounding factors, three multivariate logistic regression models were established to analyze the independent effect of Lp(a) level on the risk of DN, in which model 1 adjusted for age and gender, model 2 adjusted for age, gender, duration of T2DM and BMI, model 3 adjusted for age, gender, duration of T2DM, BMI, SBP, DBP, HbA1c and lipid-lowering drugs usage. Here, LPA is linked to type 2 diabetes mellitus.