The SNPs CYP2J2-rs76271683 and CYP2C8-rs11572177 have been associated with an increased risk of GDM, while the missense variant rs57699806 in EPHX2 has been associated with an increased risk of GDM and higher 1hPG and GAUC at OGTT (100). The gene discussed is EPHX2; the disease is gestational diabetes.