GPR119 is mainly expressed in gastrointestinal secretory cells and pancreatic beta cells (Chu et al., 2007), when GPR119 is activated, it will increase the accumulation of cAMP, increase the secretion of glucagon-like peptide-1 (GLP-1), glucose-dependent insulin peptide (GIP) or insulin (Dhayal and Morgan, 2010; Chepurny et al., 2016), which regulates the homeostasis of blood sugar levels in patients with type 2 diabetes. This evidence concerns the gene GPR119 and type 2 diabetes mellitus.