Valsartan is more specific in inhibiting angiotensin II receptor type 1 than telmisartan and exhibits different pharmacological effects, For example, telmisartan promotes insulin secretion in rat islets, whereas valsartan does not (Liu et al., 2021), and has a better therapeutic effect in hypertension than valsartan (Takagi et al., 2013). The gene discussed is AGTR1; the disease is hypertensive disorder.