PFKM is a known subtype of PFK in humans, Jia et al. [46] found that in OS, lncRNA XLOC_005950 is upregulated and acts as a molecular sponge for miR-542-3p, upregulating the expression of downstream target gene PFKM, thereby promoting glycolysis rate and tumour progression. The gene discussed is PFKM; the disease is neoplasm.