TNF and malaria: Moreover, in a murine model of cerebral malaria, treatment with CBD (30 mg/kg/d for 3 days, in addition to the traditional anti-malaria drug Artesunate) inhibited the increase in proinflammatory cytokines (TNFα and IL-6) in the hippocampus and prefrontal cortex and subsequently restored malaria-induced memory deficits (Campos et al., 2015).