Conversely, decreased concentrations of CD19, IL-4, IL-6, IL-10, TNF-α, and INF-γ were inversely correlated with the occurrence of hypertension comorbid with stroke (CD19: P = 0.039, χ2 = 4.277; IL-4: P < 0.001, χ2 = 39.200; IL-6: P < 0.001, χ2 = 40.422; IL-10: P < 0.001, χ2 = 30.744; TNF-α: P < 0.001, χ2 = 41.178; INF-γ: P < 0.001, χ2 = 40.468) (Fig. 2A). Here, TNF is linked to hypertensive disorder.