TNF and atrial fibrillation: Furthermore, reduced levels of LDL, HDL, IL-4, IL-6, IL-10, TNF-α, and INF-γ were negatively correlated with atrial fibrillation comorbidity in stroke patients (LDL: P = 0.006, χ2 = 8.250; HDL: P = 0.034, χ2 = 4.496; IL-4: P = 0.007, χ2 = 6.889; IL-6: P = 0.007, χ2 = 6.857; IL-10: P = 0.031, χ2 = 4.823; TNF-α: P = 0.007, χ2 = 7.468; INF-γ: P = 0.007, χ2 = 7.222) (Fig. 2D).