TNF and diabetes mellitus: Conversely, reduced concentrations of CD4, IL-4, IL-6, IL-10, TNF-α, and INF-γ were negatively correlated with diabetes in stroke patients (CD4: P = 0.032, χ2 = 5.281; IL-4: P < 0.001, χ2 = 22.293; IL-6: P < 0.001, χ2 = 22.153; IL-10: P < 0.001, χ2 = 18.807; TNF-α: P < 0.001, χ2 = 23.495; INF-γ: P = 0.003, χ2 = 8.396) (Fig. 2B).