PRTN3 and anti-neutrophil cytoplasmic antibody-associated vasculitis: In addition, autoimmune serology was positive for perinuclear ANCA (p-ANCA) (the titer was 128) and negative for cytoplasmic ANCA (c-ANCA) and proteinase 3, according o the clinical manifestations and positive p-ANCA, the diagnosis of ANCA-associated vasculitis (AAV) was considered.