In addition, PT_VCAM1 (Fig. 3E, OR = 1.87, 95% CI [1.67–2.10], p = 6.9e − 27), PT_PROM1 (Fig. 2E, OR = 1.37, 95% CI [1.22–1.53], p = 2.0e − 08), and PT_MT (Fig. 3E, OR = 2.05, 95% CI [1.67–2.50], p = 1.7e − 12) were among the cell types with the highest odds for LOY after adjusting for CKD. Here, MCAT is linked to chronic kidney disease.