The ratio “AF of CD163” / “AF of CD68” was greater in OM (mean 11.4, 95%CI: 0.4–30.8) and PT area (mean 10.1, 95%CI: 0.5–32.5) compared with IM (mean 7.3, 95%CI: 0.8–14.5) or TC (mean 4.7, 95%CI: 0.7–15.1), although only difference between PT area and TC was significant (P = 0.040). Here, CD163 is linked to ocular melanoma.