It is possible that XFG may trigger some immune response which cross-reacts with FUT2 antigens due to molecular mimicry wherein the immune system mistakenly targets the FUT2 proteins while attempting to target a pathological feature of XFG, or that FUT2 antibodies observed in this study may be a marker for other systemic issues more common in XFG patients. Here, FUT2 is linked to exfoliation syndrome.