Consistently, CXCL5 was found to be upregulated in various tumor types, including Adrenocortical carcinoma (ACC), Cholangiocarcinoma (CHOL), Colon adenocarcinoma (COAD), and GBM, underscoring the upregulation of CXCL5 in GBM tissues.These findings suggest a potential association between the abnormal expression of CXCL5 and the development and progression of GBM. This evidence concerns the gene CXCL5 and glioblastoma.