BCL2 and non-small cell lung carcinoma: We also checked the protein levels of Bak and Bcl-2, and found that, compared with acacetin-treatment group, miR-34a agomir had no effect on the protein levels of both proteins, whereas protein levels of Bcl-2 had not changed in the miR-34a antagomir group, compared with the control (untreated) group (Fig. 6F) in A549 cells, indicating that inhibition of miR-34a expression could abolish the apoptotic-effects of acacetin in NSCLC cells.