TIMP2 and head and neck squamous cell carcinoma: Zhang et al. evaluated the transcriptomes of PNI in HNSCC using weighted gene coexpression network analysis and found 12 genes (TIMP2, MIR198, LAMA4, FAM198B, MIR4649, COL5A1, COL1A2, OLFML2B, MMP2, FBN1, ADAM12, and PDGFRB) were highly expressed in fibroblasts7.