Noticeably, these results were also observed in the spinal cord of the transgenic FUS mice model of ALS (unrelated to mutations in SOD1, and characterized by an aggressive ALS-like phenotype) [17], indicating a degree of pathological convergence of the different genotypes of familial ALS, at least from the lipidomic perspective [7]. Here, SOD1 is linked to amyotrophic lateral sclerosis.