AFP and hepatocellular carcinoma: Multifactorial analysis involving these variables showed that hepatocirrhosis (HR 1.61; 95% CI 1.20–2.16; p = 0.002), Child–Pugh classification (HR 2.12; 95% CI 1.32–3.38; p = 0.002), AFP (HR 1.00; 95% CI 1.00–1.00; p < 0.001), and LMR (HR 1.01; 95% CI 1.00–1.02; p = 0.010), tumor diameter (HR 1.01; 95% CI 1.01–1.01; p < 0.001), BCLC staging (HR 2.69; 95% CI 1.08–6.72; p = 0.034), and MVI (HR 2.37; 95% CI 1.83–3.06; p < 0.001) were independent prognostic factors for OS in patients with HCC.