Currently, many clinical trials are evaluating the efficacy of different treatments involving the gut–liver axis, including FMT [99,100], drugs (eg, anti-alcoholism drug disulfiram) [101], diet [102], probiotics [103–106], synbiotics [107], antibiotics [108], fibroblast growth factor 19 analog (aldafermin or NGM282) [109], and physical activity [110]. Here, FGF19 is linked to alcohol drinking.