Inhibition of bile acid (BA)-converting Clostridium species (eg, Clostridium scindens) that are responsible for converting primary BAs (PBAs) to secondary BAs (SBAs) can increase the expression of CXCL16 on LSECs to attract the infiltration of hepatic CXCR6+ NKT cells to inhibit liver cancer progression [23]. Here, CXCL16 is linked to liver cancer.