CXXC5 and chronic myelogenous leukemia, BCR-ABL1 positive: In addition, CXXC5 expression was positively correlated with infiltration of CD8+ T cells, resting memory CD4+ T cells, resting NK cells, activated dendritic cells, and memory B cells, suggesting that CXXC5 may be involved in CML anti-tumor immunity (Figure 6C).