Regarding reproductive disorders associated with PCOS (hyperandrogenism, high serum LH levels, blockage of the estrous cycle in the diestrus phase, anovulation, ovarian cysts, and infertility), our results showed that the aqueous extract of A. ampeloprasum stimulated the resumption of the estrous cycle, improved ovarian dynamics, decreased serum LH and testosterone levels, and slightly increased serum estradiol levels. This evidence concerns the gene PLOD1 and polycystic ovary syndrome.