Beyond the well‐known HSP90 clients like the tumor suppressor p53 and the oncoprotein SRC, a myriad of other HSP90 clients, including protein kinases, telomerase, hypoxia‐inducible factor 1α (HIF‐1α), and Akt, are deeply entrenched in the processes that fuel tumor growth.23, 111, 112, 113. The gene discussed is AKT1; the disease is neoplasm.