There is an overlap of AD, PD, and TDP-43 pathology in highly exposed MMC children and young adults, and the overlap is similar to the one shown in USA elderly subjects five to seven decades later (Kovacs et al., 2013; Wennberg et al., 2019; Karanth et al., 2020; Robinson et al., 2023). The gene discussed is TARDBP; the disease is Alzheimer disease.