After adjusting for sex, age, drinking status, smoking status, weight, ALB, ALT, AST, ALP, CREA, UA, TG, LDL, HDL, urea, CHD, ischemic cerebrovascular disease, hypertension, and DM, we found no significant interactions across these subgroups (Figure 3, all P for interaction >0.05). The gene discussed is GPT; the disease is hypertensive disorder.