At CML occurrence, WBC increase was the most common laboratory sign, observed in 38 of 42 cases with available data (4–43, 45–51), followed by anemia in 17/42 (6, 16, 17, 23, 27, 31, 37–39, 45, 50); basophilia in 17–42 (6, 13, 17, 23, 27, 35, 38, 41, 45, 47–50); PTL decrease in 9/42 (13, 27, 37–39, 45); leukoerythroblastosis in 7/42 (17, 31, 43, 45, 48); PTL increase in 6/42 (6, 22, 23, 37, 39, 48); eosinophilia in 6/42 (13, 41, 45, 47, 48), and LDH increase in 2/42 (27, 48). This evidence concerns the gene PNLIP and chronic myelogenous leukemia, BCR-ABL1 positive.