NTRK1 and neoplasm: Next, CPL304110 selectivity was analyzed on seven kinases; the results showed that CPL304110 had the highest activity against kinases that share homology with FGFRs (KDR and PDGFRβ) and others that play an important role in tumor development and progression (AURKA, FLT3, IGF1R, JAK2, and TRKA).