In 1,375 pT2-4 carcinomas, the average EpCAM staining intensity was again intermediate (18.3 ± 12.3) and ranged between the values seen in pTa G2 low grade (p<0.001 for pTa G2 low grade vs. pT2-4) and pTa G3 tumors (p=0.071 for pTa G2 high grade vs. pT2-4). The gene discussed is EPCAM; the disease is carcinoma.