ESR1 and neoplasm: To confirm the oestrogen‐mediated tumour responses observed in our previous studies14, 15 as well as to get a brief insight of spatial gene expression pattern in our ST datasets, we performed cell cycle analysis and examined the expressions of ESR1, PGR, and MKI67 genes (encoding the three important markers ER, PR, and Ki67, respectively) (Figures 2A and B).