GFAP and AIDS: The number of GFAP reactive astrocytes increased in the 2 AIDS groups and was greatest in the HIVE group (p < 0.05).The increase in GFAP reactive astrocytes for both NCN HIV and HIVE was greatest in the CA4 region where it was 4‐fold and 6‐fold greater than controlsLN3‐positive microglia were rare or absent in controls and increased in AIDS brains.