We observed directionally concordant associations with MS in both the discovery and replication cohorts for 28/34 (82.4%) proteins, including most of the proteins increased in MS in UKB (IL17RB, NEFL, CTSF, MERTK, GFAP, LILRB4, and LAMP3), but not IL15. The gene discussed is CTSF; the disease is myeloid sarcoma.