The decision to initiate an external, infection-related consultation could, for a simplified example, be driven by a combination of several factors: changes in infection-related laboratory results such as an increase in C-reactive protein (CRP), deteriorating vital signs (e.g. increase in heart rate and decrease in blood pressure), results in imaging suggesting the presence of an infection (e.g. pulmonary infiltrates on chest x-ray images), and the lack of a (timely) response to administered antimicrobial therapy. Here, CRP is linked to infection.