In animal models, we used LAD ligation to establish an experimental MI model, and we found that in the absence of baseline CoQ10 deficiency and the use of statins that affect CoQ10 levels, the single use of CoQ10 treatment showed a trend of improved survival rate, significantly reduced BNP levels, improved cardiac dysfunction, and adverse cardiac remodeling induced by MI, further supporting that early supplementation with CoQ10 is beneficial for improving MI prognosis. This evidence concerns the gene NPPB and hyperinsulinemic hypoglycemia, familial, 4.