Once the logFC values are considered, however, in BRCA the negative correlations are observed between MDM4 and tumor cell metabolism such as cellular glucuronidation (GO:0052695), lipid catabolic process (GO:0044242), and alcohol dehydrogenase (NADP+) activity (GO:0008106) (Fig. 6B). The gene discussed is AKR1A1; the disease is neoplasm.