Age, BMI, comorbidities (hypertension, cardiovascular disease, cerebrovascular disease), pleural effusion, bilateral lung lesions, body temperature, systolic pressure, respiratory rate, pulse, SpO2, WBC count, ANC count, LYM count, HB, CRP, PCT, TBIL, AST, ALB, BUN, Cr, eGFR, UA, Na+, Cl−, TC, HDL, LDL, LDH, and D-Dimer were discovered to have statistical differences between the clinical deterioration group and non-clinical deterioration group (P < 0.05) (Table 1). This evidence concerns the gene CRP and Pleural effusion.