In addition, in alcoholic hepatitis rat models, glycyrrhizin exhibits inhibitory effects on the secretion of human growth-regulated oncogene/keratinocyte chemoattractant (GRO/KC), granulocyte-macrophage colony-stimulating factor (GM-CSF), vascular endothelial growth factor (VEGF), and intercellular adhesion molecule 1 (ICAM-1). The gene discussed is CALCA; the disease is alcoholic hepatitis.