Expression levels were compared in two B-cell lymphoma cell lines [WSU-DLCL2, a t(14;18)-positive cell line, and SU-DHL-8, a t(14;18)-negative cell line], to discriminate true BCL2 high signal (or overexpression, resulting from the translocation), in contrast to endogenous expression. This evidence concerns the gene BCL2 and B-cell non-Hodgkin lymphoma.