[18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 high resolution autoradiography followed by immunostaining with PHF-1 or Aβ antibodies on the same brain slices confirmed that the lesions labeled by the nuclear emulsion were tau aggregates, including classic AD tau tangles (Fig. 7b) and tau containing dystrophic neurites (Fig. 7c), but not Aβ plaques themselves or vessels with β-amyloid deposits (Fig. 7f). Here, PPIB is linked to Alzheimer disease.