Research on the function of the CD24/Siglec-10 axis in controlling macrophage-triggered phagocytosis using human breast cancer MCF-7 cells has demonstrated that in an in vitro co-culture system, macrophages preferentially phagocytotize CD24-/-MCF-7 cells over wild-type MCF-7 cells [29]. The gene discussed is CD24; the disease is breast cancer.