Apart from the JAK1-STAT3 cascade, IL-10 is hypothesized to boost cancer stemness through the JAK1-STAT1-NF-\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\kappa$$\end{document}κ B pathway, thereby promoting tumor progression and metastasis [102]. The gene discussed is IL10; the disease is cancer.