For this study, CML and CEL (lysine adducts) and GH-1 and MG-H1 (dicarbonyls derivatives) were designated pairs, grouped designated as CML + CEL + GH-1+ MG-H1 and finally, total as CML + CEL + GH-1+ MG-H1 + AP. The gene discussed is GH1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.