Depression-like behavior improved after treatment with (+/-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a serotonin 1A receptor agonist (5-HT1A) [26] or extract of Ophiocordyceps formosana, a Cordyceps spp. This evidence concerns the gene HTR1A and depressive symptom measurement.