Cancer vaccines are a realm of immunotherapy where selected tumor antigens are exogenously administered along with adjuvants/immunostimulants, such as granulocyte-macrophage colony-stimulating factor (GM-CSF) or interferon-gamma a, to induce the activity of APCs, mainly dendritic cells, aiming to stimulate the adaptive immune system against cancer cells. The gene discussed is IFNG; the disease is cancer.