AQP3 and Sepsis: This is in contrast to a recent study that showed that AQP3 participates in the regulation of pulmonary vascular permeability after sepsis and that the antioxidant Ss-31 has a protective effect on pulmonary vascular permeability by downregulating the expression of AQP3 and inhibiting reactive oxygen species (ROS) production, which led to increased survival in a CLP model [31].