Splenocytes prepared on days 8 and 16 post-infection with OC43 were stimulated with a panel of 37 HLA-B*0702-restricted SARS-CoV-2 CD8+ T cell epitopes previously shown to stimulate human CD8+ T cells based on IFNγ-ELISpot or ICS assays (NIAID Virus Pathogen Database and Analysis Resource; Table 3)25,89–95. Here, CD8A is linked to infection.