Additionally, YAP1 was initially proposed to define a distinct subtype itself 8 but on further analysis was found to be absent or expressed only at low levels in tumors (typically in the stroma or in the NSCLC component of mixed tumors), although a subpopulation of YAP1 positive cells may emerge in the setting of resistance9,10,20,41. Here, YAP1 is linked to non-small cell lung carcinoma.