MALAT1 expression was upregulated in ACC tissues, and it could compete with miR-497 to promote eukaryotic translation initiation factor 4E expression and thus to promote the cell cycle, and the MALAT1/miR-497/EIF4E regulatory axis might be a latent therapeutic target for ACC.[126] Urothelial carcinoma antigen l is an important lncRNA that exhibits proto-oncogene function and is highly expressed in a variety of tumors, especially in bladder cancer. Here, MALAT1 is linked to adrenal cortex carcinoma.