BCL2 and adrenal cortex carcinoma: MiR-205 was greatly less expressed in ACC tissues than in adrenocortical adenoma (ACA) and that miR-205 could inhibit apoptosis by targeting the apoptotic gene Bcl-2 to activate Bcl-2/Bax/caspase3/9.[109] MiR-205 may be implicated in the regulation of ACC growth as an oncogene.